modafinil will lessen the extent or result of mavacamten by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.

B: Can be acceptable. Both animal studies show no risk but human scientific studies not obtainable or animal experiments confirmed insignificant threats and human experiments done and showed no threat.

No withdrawal signs and symptoms ended up observed in sufferers with modafinil therapy cessation during 14 days of observation, but in people with narcolepsy, sleepiness returned.

tecovirimat will enhance the amount or effect of modafinil by affecting hepatic enzyme CYP2C19 metabolism. Use Warning/Check. Tecovirimat is actually a weak inhibitor of CYP2C8 and CYP2C19. Monitor for adverse outcomes if coadministered with delicate substrates of such enzymes.

Also, your wellbeing care Skilled might be able to let you know about approaches to prevent or reduce some of these side effects. Verify with all your health and fitness care Experienced if any of the subsequent Uncomfortable side effects continue or are bothersome or When you've got any questions on them:

saquinavir will raise the amount or result of modafinil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.

Doses as many as four hundred mg/working day, provided as one dose, happen to be nicely tolerated, but there is no reliable proof this dose confers supplemental benefit over and above that on the two hundred mg/day dose

crizotinib improves amounts of modafinil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on. Dose reduction may be needed for coadministered medication which might be predominantly metabolized by CYP3A.

cenobamate will increase the degree or effect of modafinil by impacting hepatic enzyme CYP2C19 metabolism. Modify Therapy/Monitor Carefully. Consider a dose reduction of CYP2C19 substrates, as clinically proper, when made use of concomitantly with cenobamate.

200mg Modafinil: The king of nootropics! 200mg Modafinil is definitely the gold typical In terms of crushing cognition. Many end users expertise 12+ several hours of laser-like emphasis at this dosage. Small Negative effects not prevalent, but some end users knowledge dehydration, headaches, or sleeplessness.

modafinil will improve the amount or effect of citalopram here by impacting hepatic enzyme CYP2C19 metabolism. Use Warning/Monitor. Citalopram 20 mg/working day is the most suggested dose for individuals having CYP2C19 inhibitors due to the possibility of QT prolongation.

300mg Modafinil: Again, it is a substantial Modafinil dose. So continue with caution below. You’ll obtain a simple eighteen+ several hours of laser-like focus at this dosage, but side effects may be a problem listed here – which include nausea. Break up dosing recommended throughout the day.

This drugs is on the market only using your medical professional's prescription. This solution is obtainable in the subsequent dosage kinds:

Provigil hasn't been sufficiently researched in pregnant Women of all ages and it's not known whether it is excreted in breast milk. Consult your health care provider ahead of breastfeeding. Extra Information and facts